Basidiobolomycosis (entomophthoramycosis) – Definition, Geographical distribution, Causal organisms, Investigations

September 12, 2011 | By | Reply More

Basidiobolomycosis (entomophthoramycosis) – Definition, Geographical distribution, Causal organisms, Investigations

Definition: This is a chronic subcutaneous infection of trunk and limbs.

Geographical distribution :

Most common in East and West Africa and Southeast Asia.

Causal organism and habitat :

  • Basidiobolus ranarum (B. meristosporus, B. haptosporus).
  • Decomposing vegetation, soil.
  • Intestines of frogs, toads, lizards and other small reptiles.

Essential investigations

Microscopy

In histopathological sections wide, irregular, non-septate filaments or hyphal fragments can be seen. Hyphae are visualized best with haematoxylin and eosin staining.

Culture

Culture specimens on glucose peptone agar at 30°C. Identifiable colonies should be obtained in less than 1 week. Flat, spreading, yellow-grey to buff, wrinkled or radially folded, waxy surface with short aerial mycelium. Characteristic ballistospores forcibly discharged to the lid of the petri dish. Secondary spores may be formed on the end of swollen hyphae emerging from the germinated spore or ballistospores may develop endospores.

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Category: Medical, Pathology

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