RSSCategory: Pharmacology

Classification of non-steroidal anti inflammatory drugs

Classification of non-steroidal anti inflammatory drugs

Classification of non-steroidal anti inflammatory drugs I. Salicylates and their congeners Acetyl salicylic acid (ASPIRIN, DISPRIN) 300-600 mg/day Sodium salicylate 1.5-6 g/day Salicylamide (SALAMIDE) 300-600 mg TDS-QID Diflunisal (DOLOBID) 500 mg BD-TDS II. Pyrazolone derivatives Phenylbutazone (ZOLANDIN) 200-600 mg/day Oxyphenbutazone (SIORIL) 200-600 mg/day III. Indole derivatives Indomethacin (INDOCAP) 25-50 mg BD-TDS Sulindac (CLINORIL) 100-200 mg […]

September 19, 2012 | By | Reply More
Treatment of Acute Barbiturate Poisoning

Treatment of Acute Barbiturate Poisoning

Treatment of Acute Barbiturate Poisoning • Gastric lavage to remove unabsorbed drug. Emesis can be produced by apomorphine and activated charcoal is administered to adsorb the unabsorbed drug. • Maintenance of respiration: Oxygen inhalation. Enotracheal intubation or tracheostomy. Mechanical ventilation. • Intravenous fluids. • Forced diuresis: Diuretics like mannitol and furosemide can be used. • […]

September 19, 2012 | By | Reply More
Classification of general anaesthetics

Classification of general anaesthetics

Classification of general anaesthetics I. Inhalational anaesthetics i. Gases Nitrous oxide 70-80% with other agents Cyclopropane 5-25% ii. Volatile liquids Ether (Diethyl ether) 3-10% Trichloroethylene (TRILENE) 0.25-0.75% Halothane (FLUOTHANE) 0.5-2.0% Methoxyflurane (PENTHRANE) 0.1-0.3% Enflurane (ETHRANE) 1-3.0% Isoflurane (FORANE) 0.8-2.0% II. Intravenous anaesthetics i. Ultra short acting barbiturates Hexobarbitone (sodium salt) Thiopentone sodium 3-5 mg/kg as […]

May 25, 2012 | By | Reply More
What is Pharmacokinetics

What is Pharmacokinetics

What is Pharmacokinetics Pharmacokinetics is the study, which determines the rapidity and concentration of the drug in the body and its duration of appearance at the target organ, i.e. onset, time of peak action and duration of action and by these also determine the route(s) and frequency of administration of drug.  

May 25, 2012 | By | Reply More
Rational use of drugs

Rational use of drugs

Rational use of drugs Rational use of drugs means using drugs which are safe and effective. These drugs should be available at reasonable prices and could be stored conveniently. The drug should be the appropriate drug for the disease, should be administered at the right dose for the right period of time. Following factors lead […]

May 25, 2012 | By | Reply More
SOLID DOSAGE FORM (INTERNAL USE)  OF DRUGS

SOLID DOSAGE FORM (INTERNAL USE) OF DRUGS

SOLID DOSAGE FORM (INTERNAL USE)  OF DRUGS Capsules: These are small gelatin contains shells. Capsules are of two types – hard & soft capsules. Hard capsules are used for powdered drugs e.g. capsules ampicillin, tetracycline. In hard capsules, certain sustained released substance, which gradually release the drug in the respiratory tract (e.g. cap. theophylline). Soft […]

May 25, 2012 | By | Reply More
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