Definition Cheilitis granulomatosa is a rare chronic disorder of the lips.
Clinical features It presents as a painless, persistent, and diffuse swelling of one or both lips (Fig.). Small vesicles, erosions, and scaling may occur. It is thought that cheilitis granulomatosa is a monosymptomatic form of Melkersson–Rosenthal syndrome. Laboratory tests Histopathological examination.
Differential diagnosis Cheilitis glandularis, Crohn disease, sarcoidosis, cystic fibrosis, lymphangioma, angioneurotic edema.
Treatment Topical or systemic steroids, tetracyclines. Plastic surgery in severe cases.