Dentine formation (dentinogenesis)

December 20, 2011 | By | Reply More

Dentine formation (dentinogenesis)

  • Differentiation of odontoblast cells

At the late bell stage the inner enamel epithelium induces cells at the periphery of the dental papilla to differentiate into columnar odontoblast cells.

The odontoblast cells begin to secrete an unmineralised dentine matrix. As more dentine matrix is deposited, the odontoblast cells retreat in the direction of the pulp leaving an elongated process known as the odontoblast process. The dentine matrix formed prior to mineralization is termed predentine. A narrow layer of predentine is always present on the surface of the pulp.

Mineralisation of dentine begins when the predentine is approximately 5 ìm thick. Spherical zones of hydroxyapatite called calcospherites are formed within the dentine matrix. Mineralisation of the dentine matrix starts at random points and eventually these calcospherites fuse together to form mineralised dentine.

Dentinal tubules form around each odontoblast process. The odontoblasts retreat in S-shaped curves towards the dental papilla. The first layer of mineralised dentine is called mantle dentine and the remaining bulk of the mineralised dentine is known as circumpulpal dentine.

Tags: , , , , , , , , , , , , ,

Category: Dental, Oral Anatomy, Pedodontics

WARNING: Any unauthorised use or reproduction of content for commercial or any purposes is strictly prohibited and constitutes copyright infringement liable to legal action.