Drug-Induced Gingival Overgrowth: Definition, Etiology, Clinical features, Differential diagnosis, Treatment
Drug-Induced Gingival Overgrowth: Definition,Etiology, Clinical features, Differential diagnosis, Treatment
Definition: Drug-induced gingival overgrowth is a relatively common disorder of the gingiva due to several drugs.
Etiology: The most common drugs associated with the condition are phenytoin, ciclosporin, and calcium channel blockers.
- The gingival overgrowth is usually related to the dose of the drug, the duration of therapy, the serum concentration, and the presence of dental plaque.
- Clinically, both marginal gingiva and interdental papillae appear enlarged and firm, with a surface that may be smooth, stippled, or lobulated, with little or no inflammation.
- The gingival overgrowth may be localized or generalized and can partially or entirely cover the crown of the teeth.
- In severe cases, difficulties in mastication and speech may occur.
- The diagnosis is made on the basis of the medical history and the clinical features.
- Hereditary gingival fibromatosis
- Mouth breathing gingivitis
- Crohn disease
- Improvement of oral hygiene
- discontinuation of the offending drug