Erythroplakia: Definition, Etiology, Clinical features, Differential diagnosis, Treatment of Erythroplakia
Erythroplakia: precancerous and premalignant lesion
Erythroplakia, or Queyrat erythroplasia, is a premalignant lesion frequently occurring on the glans penis, and rarely on the oral mucosa. It is defined as a red, nonspecific patch or plaque that cannot be classified clinically and pathologically under any other disease.
- It appears as a usually asymptomatic, fiery red, well demarcated plaque, with a smooth and velvety surface.
- The red lesions may be associated with white spots or small plaques.
- The floor of the mouth, retromolar area, soft palate, and tongue are the most common sites of involvement.
- Erythroplakia occurs more frequently between the ages of 50 and 70 years.
- Over 91% of erythroplakias histologically demonstrate severe dysplasia, carcinoma in situ, or early invasive squamous-cell carcinoma at the time of diagnosis.
Laboratory tests Histopathological examination.
- Erythematous candidiasis,
- lichen planus,
- discoid lupus erythematous,
- early squamous-cell carcinoma,
- local irritation.