Erythroplakia: Definition, Etiology, Clinical features, Differential diagnosis, Treatment of Erythroplakia

September 11, 2011 | By | Reply More

Erythroplakia: precancerous and premalignant lesion

Definition

Erythroplakia, or Queyrat erythroplasia, is a premalignant lesion frequently occurring on the glans penis, and rarely on the oral mucosa. It is defined as a red, nonspecific patch or plaque that cannot be classified clinically and pathologically under any other disease.

 Etiology Unknown.

Clinical features

  • It appears as a usually asymptomatic, fiery red, well demarcated plaque, with a smooth and velvety surface.
  • The red lesions may be associated with white spots or small plaques.
  • The floor of the mouth, retromolar area, soft palate, and tongue are the most common sites of involvement.
  • Erythroplakia occurs more frequently between the ages of 50 and 70 years.
  • Over 91% of erythroplakias histologically demonstrate severe dysplasia, carcinoma in situ, or early invasive squamous-cell carcinoma at the time of diagnosis.

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Laboratory tests Histopathological examination.

 Differential diagnosis

  • Erythematous candidiasis,
  •  lichen planus,
  • discoid lupus erythematous,
  • early squamous-cell carcinoma,
  •  local irritation.

 Treatment  Surgical excision.

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Category: Dental, Oral Pathology

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