Hereditary Gingival Fibromatosis: Definition, Etiology, Clinical features, Differential diagnosis, Treatment of Hereditary Gingival Fibromatosis

October 1, 2011 | By | Reply More

Hereditary Gingival Fibromatosis: Definition, Etiology, Clinical features, Differential diagnosis, Treatment of Hereditary Gingival Fibromatosis

Definition: Hereditary gingival fibromatosis is a unique gingival enlargement caused by collagenous proliferation of the fibrous connective tissue of the gingivae.

Etiology: Genetic. It is transmitted as an autosomal dominant or rarely as an autosomal recessive trait.

Clinical features :

  • The disorder usually begins before age 15 years in both sexes.
  • The gingival enlargement is usually generalized, but less commonly may be localized in one or two quadrants.
  • The gingiva are firm, smooth, and occasionally papillary or nodular, with no or only minimal inflammation, and a normal color.
  • The teeth may be partially or completely covered by the overgrown gingiva.
  • Delay or failure in teeth eruption may also be seen.
  • Although either jaw may be involved, the maxillary gingiva are more frequently and severely affected.
  • The diagnosis is mainly based on the history and the clinical features.

Laboratory tests: Histopathological examination.

Differential diagnosis:

  • Drug-related gingival overgrowth,
  • gingival fibromatosis associated with several genetic syndromes,
  • Crohn disease,
  • amyloidosis,
  • leukemia.

Treatment: Gingivectomy, good oral hygiene.

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Category: Dental, Medical, Oral Pathology, Oral Surgery, Pathology

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