Non-allergic rhinitis with eosinophilia syndrome (NARES): Cause, Symptoms, Treatment
Non-allergic rhinitis with eosinophilia syndrome (NARES): NARES, or eosinophilic rhinitis (ie, perennial intrinsic rhinitis) accounts for as many as 20% of rhinitis diagnosis. Some researchers believe that this condition may be a precursor to the aspirin triad of intrinsic asthma, nasal polyposis, and aspirin intolerance. Abnormal prostaglandin metabolism has been implicated as a cause of NARES.
Eosinophil counts are elevated in approximately 20% of nasal smears in the general population; however, not everyone with eosinophilia has symptoms of rhinitis. A distinguishing feature of NARES is the presence of eosinophils, usually 10-20% on nasal smears.
In general, patients with NARES present with-
- nasal congestion,
- nasal pruritus, and
A wide variety of etiologies are involved in non-allergic rhinitis. Therefore, treatment options should not be implemented randomly. Instead, they should be primarily aimed at resolving the underlying causative physiology. It is also valuable to distinguish between allergic and non-allergic rhinitis before a treatment method is chosen.