Odontogenic keratocyst : Pathogenesis ,feature and Treatment

April 8, 2012 | By | Reply More

Odontogenic keratocyst : Pathogenesis ,feature and Treatment

Pathogenesis:
1. The tooth germ is destroyed or liquefied by certain stimulation before formation of crown or calcification.
2. So, the tooth germ is missing leading to missing teeth.

Clinical feature:
1. Age: 20-30 years
2. Sex: No predilection
3. Site: Mandible in 75% cases
4. Grows around a tooth
5. Spreads extensively along marrow space before expanding the jaw
6. Asymptomatic unless infected
7. Expansion occurs inward to destroy the cortical plate
8. Frequently recur after enucleation

Radiological feature:
1. Well defined radiolucent area
2. Rounded or scalloped margin
3. Some are unilocular but majority are multilocular

 

Histopathological feature:
1. Epithelial lining of uniform thickness
2. Flat lower border of epithelium
3. Cyst lining is typically more folded
4. Epithelial lining weakly attached to the fibrous wall
5. Thin fibrous wall
6. Satellite cysts in the wall
7. Inflammatory cells typically absent or scanty

Treatment:
1. Enucleation
2. Mursupialization followed by enucleation
3. Resection

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Category: Dental, Oral Pathology

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