Pathophysiology of Nephrotic Syndrome (NS)

September 4, 2011 | By | Reply More

Pathophysiology of Nephrotic  Syndrome (NS)


Fundamental and highly important change of pathophysiology.


2.Hypoproteinemia (mainly albumin)

3.Edema: Nephrotic edema  (pitting edema)

 Hypoproteinemia     plasma   oncotic pressure is diminished,   result in a shift of fluid from  the vascular to the interstitial  compartment and plasmavolume↓→the activation of the renin-angiotensin–aldo-sterone   system→ tubular sodium chloride reabsorp-tion↑.

4. Hyperlipidemia (Hyper-cholesterolemia)

Ch↑, TG↑, LDL-ch↑,VLDL-ch↑.

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Category: Medicine, Pathology, Physiology

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