Tooth extraction in a patient of chemotherapy
The major organ system affected by cytotoxic chemotherapy is the hematopoietic system. When a patient receives chemotherapy, the white cell count and platelets may be expected to decrease in about 7—10 days. If the patient’s absolute neutrophil count (calculated by multiplying the white cell count by the number of neutrophils in the differential count and dividing by 100) drops below 500 neutrophils, the patient is considered neutropenic and at risk for infection. If the platelet count drops below 50,000, the patient is at risk for bleeding.
Dental procedures should be scheduled, if possible, 2 weeks before planned chemotherapy or after the counts begin to recover, usually 14 days for white cells and 21 days for platelets. Dental treatment should be attempted only after consultation and in coordination with the patient’s physician and after the patient has had a CBC.