Treatment of Acute Barbiturate Poisoning

September 19, 2012 | By | Reply More

Treatment of Acute Barbiturate Poisoning

• Gastric lavage to remove unabsorbed drug. Emesis can be produced by apomorphine and activated charcoal is administered to adsorb the unabsorbed drug.
• Maintenance of respiration:

  1. Oxygen inhalation.
  2. Enotracheal intubation or tracheostomy.
  3. Mechanical ventilation.

• Intravenous fluids.
• Forced diuresis: Diuretics like mannitol and furosemide can be used.
• Alkalinization.
• Prophylactic antimicrobial therapy to avoid any secondary infection e.g. pneumonia and infection due to tracheostomy or urinary catheterization.
• Dialysis (peritoneal or haemodialysis).

Category: Medicine, Pharmacology

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