Vesiculobullous Lesions : definitions and examples
Vesiculobullous diseases are a distinct group of oral disorders characterized by the formation of vesicles or bullae. Clinicians must bear in mind that it is uncommon to see vesicles or bullae intraorally, as they soon rupture, leaving erosions or ulcers.
This group includes viral diseases, autoimmune mucocutaneous diseases, diseases that probably have an immunologically mediated mechanism, and genetic diseases.
The diagnosis of vesiculobullous diseases should be made on clinical, histopathological, and immunological grounds.
Examples of Vesiculobullous Lesions:
- Primary herpetic gingivostomatitis,
- Secondary herpetic stomatitis,
- Herpes zoster,
- Hand-foot-and-mouth disease,
- Erythema multiforme,
- Stevens–Johnson syndrome,
- Toxic epidermal necrolysis,
- Cicatricial pemphigoid,
- Bullous pemphigoid,
- Pemphigoid gestationis,
- Linear IgA disease,
- Dermatitis herpetiformis,
- Bullous lichen planus,
- Epidermolysis bullosa,
- Epidermolysis bullosa acquisita,
- Angina bullosa hemorrhagica,